Archive for April 10th, 2010
Intentional weight loss helps, not harms, seniors.
The outcome of a study scheduled to appear in the print issue of the Journal of Gerontology: Medical Sciences contradicts the concerns raised by previous studies that deliberate weight loss among older individuals could increase the risk of death.
Weight reduction aids in lowering high blood pressure, elevated cholesterol and high fasting glucose levels, all of which can increase with aging, yet some health care practitioners have hesitated recommending weight loss to older individuals due to findings that associated weight reduction with increased mortality. However, the studies upon which these conclusions were based did not address whether weight loss was intentional or due to underlying disease.
M. Kyla Shea, PhD and her associates at Wake Forest University Baptist Medical Center analyzed data from 318 arthritic men and women over the age of 60 who participated in a randomized trial that evaluated the effects of dieting and/or exercise on physical function. Known cardiovascular disease, severe hypertension, chronic obstructive pulmonary disease, and other conditions that could limit participation in regular exercise were criteria for exclusion. The 159 subjects in the weight loss diet and diet plus exercise intervention groups lost an average of 10.5 pounds over an 18.5 month period, while the exercise only group and the healthy lifestyle control participants lost an average of 3.1 pounds.
The current study analyzed deaths that occurred up to 8 years after the trial’s conclusion. Dr Shea and colleagues discovered a correlation between weight loss and increased survival. Fifteen deaths occurred among those assigned to weight loss diet interventions, compared with 30 in the remainder of the participants. “It was an unusually strong and surprising finding,” stated Dr Shea, who is a research associate in Wake Forest’s Department of Internal Medicine, Section on Gerontology and Geriatric Medicine. “Overall, we found that there were far fewer deaths – half the number – in the group of participants that lost weight compared to the group that did not.”
“These were the seniors living out in the community, getting around and doing their daily tasks just like your neighbor,” noted coauthor Stephen B. Kritchevsky, PhD, who is the director of the J. Paul Sticht Center on Aging. “All were overweight and dealing with the signs of aging when the study started.”
“For years, the medical community has relied on multiple epidemiological studies that suggested that older people who lost weight were more likely to die,” he remarked. “Weight loss in old folks is just understood to be a bad prognostic sign. The data that people have been using has been unable to separate the cause and effect of the weight loss, however, and our study suggests that the weight loss they’ve been studying may be the result of other health problems and not of intentional weight loss.”
“This study puts to rest a lot of unfounded concerns about how to address the epidemic of obesity among our older adults,” he concluded.
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Health Concern Life Extension Highlight
Obesity
The risk of death from all causes, including cardiovascular disease and cancer, increases with rising obesity in both men and women in all age groups, and the risk associated with a high BMI is greater for whites than for blacks (Calle et al 1999).
Obesity increases the risk of developing metabolic syndrome and coronary heart disease (Shirai 2004); type 2 diabetes (Mensah et al 2004); osteoarthritis of major load-bearing joints, such as the knee (Felson et al 1997); hypertension (high blood pressure); sleep apnea (periods of suspended breathing during sleep) (Wolk et al 2003); and gall bladder disease (Petroni 2000).
The International Agency for Research on Cancer has classified obesity as a critical causal risk factor for cancers of the colon, breast (postmenopausal women), endometrium, kidney (renal cell), and esophagus (adenocarcinoma) (Calle et al 2004).
A study reported in the Journal of the American Medical Association suggests that obesity causes 111,909 deaths annually (Flegal et al 2005), while epidemiological evidence shows that a lower body weight is associated with lower mortality risk (Stevens 2000). In the well-known Framingham Heart Study, risk of death increased by 1 percent for each extra pound (0.45 kg) of weight between age 30 and 42 and increased by 2 percent between age 50 and 62 (Solomon et al 1997; Kopelman 2000).
In order to prevail against your body’s innate propensity to store fat, you must restore fat-reducing hormones such as DHEA and testosterone lost to aging, and suppress hormones such as insulin and estrogen, which promote body fat. You’ll want to enhance insulin sensitivity and maintain a youthful metabolic rate so that your cells are able to release stored fat.
Read Full Post | Make a Comment ( None so far )Study: Low levels of vitamin D linked to higher rates of asthma in African-American kids
Researchers at Children’s National Medical Center have discovered that African American children with asthma in metropolitan Washington, DC, are significantly more likely to have low levels of vitamin D than healthy African American children (see also Children’s National Medical Center).
This study supports recent research that suggests vitamin D plays a greater role in the body than just keeping bones healthy. Vitamin D deficiency has been recently linked to a variety of non-bone related diseases including depression, autoimmune disorders, and now asthma.
“It’s been well-documented that as a group, African Americans are more likely than other racial groups to have low levels of vitamin D,” said Robert Freishtat, MD, MPH, an emergency medicine physician and lead author on the study. “But we were shocked to see that almost all of the African American children with asthma that we tested had low vitamin D levels. After adjusting for differences in age, weight, and the time of year of the testing, the odds of these kids with asthma being vitamin D deficient were nearly twenty times those of healthy kids.”
The study took a one-time measurement of vitamin D in the blood of 85 African American children with asthma, who were between 6 and 20 years old. Additionally, the researchers measured the vitamin D levels of 21 healthy African American children between the ages of 6 and 9 years of age. The research team found that 86 percent of the children in the study with asthma had insufficient levels of vitamin D, while only 19 percent of non-asthmatics had these low levels.
These findings may mean that low vitamin D levels have more serious effects on a child’s lung health than previously believed. Though more research is needed to establish definitively how vitamin D deficiency can contribute to asthma, parents can ensure that their children receive healthier amounts of vitamin D by following the current USDA guidelines for milk consumption and seeking a doctor’s advice about multivitamins.
“The District of Columbia has among the highest rates of pediatric asthma in the United States, and we’re working to find out why,” says Stephen Teach, MD, MPH, senior author of the study. “For African American kids with asthma, vitamin D testing and ensuring adequate vitamin D intake may need to become necessary steps in their primary care.”
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